The code breaker : Jennifer Doudna, gene editing, and the future of the human race / Walter Isaacson.

Book

Isaacson, Walter, author.

First Simon & Schuster hardcover edition.

New York : Simon & Schuster, 2021.

xix, 536 pages : illustrations (chiefly color) ; 25 cm

An account of how the pioneering scientist Jennifer Doudna, along with her colleagues and rivals, launched a revolution that will allow us to cure diseases, fend off viruses, and enhance our children.

Doudna, Jennifer A.

Watson, James D., 1928-

Biochemists -- United States -- Biography.

Women biochemists -- United States -- Biography.

Nobel Prize winners -- Biography.

Women scientists -- United States -- Biography.

CRISPR (Genetics)

Gene editing.

Gene editing -- Moral and ethical aspects.

Geneticists.

DNA.

Human genome.

Academic-industrial collaboration.

Biotechnology.

Includes bibliographical references ([487]-516) and index.

Introduction. Into the breach -- Part one. The origins of life. Hilo ; The gene ; DNA ; The education of a biochemist ; The human genome ; RNA ; Twists and folds ; Berkeley -- Part two. CRISPR. Clustered repeats ; The Free Speech Movement Café ; Jumping in ; The yogurt makers ; Genentech ; The lab ; Caribou ; Emmanuelle Charpentier ; CRISPR-Cas9 ; Science, 2012 ; Dueling presentations -- Part three. Gene editing. A human tool ; The race ; Feng Zhang ; George Church ; Zhang tackles CRISPR ; Doudna joins the race ; Photo finish ; Doudna's final sprint ; Forming companies ; Mon amie ; The heroes of CRISPR ; Patents -- Part four. CRISPR in action. Therapies ; Biohacking ; DARPA and anti-CRISPR -- Part five. Public scientist. Rules of the road ; Doudna steps in -- Part six. CRISPR babies. He Jiankui ; The Hong Kong summit ; Acceptance -- Part seven. Moral questions. Red lines ; Thought experiments ; Who should decide? ; Doudna's ethical journey -- Part eight. Dispatches from the front. Quebec ; I learn to edit ; Watson revisited ; Doudna pays a visit -- Part nine. Coronavirus. Call to arms ; Testing ; The Berkeley lab ; Mammoth and Sherlock ; Coronavirus tests ; Vaccines ; CRISPR cures ; Cold Spring Harbor virtual ; The Nobel Prize.

2020043552

9781982115852 (hardcover)

1982115858 (hardcover)

9781982115869 (paperback)

1982115866 (paperback)

1187220557

3820525

70

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